our mission
Tools and products backed by science
Whether you're just passionate about taking care of your own skin, or an experienced esthetician looking to take the best care of your clients, we have the expertise and resources to help you get the best self care possible.
P.E.T.® allows the penetration of anti-aging ingredients to the regenerative layer of the epidermis where new cells are created. When new cells are fed and nourished with antioxidants, peptides and other active ingredients, the skin will not only look and feel healthier, it will truly be healthier.
Hear from our clients and customers to see what helps them achieve their best skin!
Born from a biomedical breakthrough, SESHA Skin Therapy was founded by Harvard- and MIT-educated scientist Dr. Dean Hsieh, whose discovery of Permeation Enhancement Technology (P.E.T.®) helped advance ingredient delivery through the skin—technology later used in an FDA-approved pharmaceutical product (2002). During early testing, researchers uncovered something remarkable: P.E.T.® could also help prevent and restore visible skin damage by helping key actives reach where they matter most.
Since launching our first products in 1996—SESHA has continued to expand into a complete line of science-based, results-driven skincare with anti-aging solutions for every skin type and every age.
In 1996, from the idea that our skin’s aging process can be significantly slowed if active ingredients are allowed to penetrate and feed our regenerative living cells, SESHA SKIN THERAPY’s first two products were born – the A.C.E. Cream and A.C.E. Emulsion. Since then, SESHA SKIN THERAPY has extended and expanded it’s anti-aging line to include levels of treatment for all types of skin and for all ages.
*Testim ®, Auxilium Pharmaceuticals
I had Mohs surgery on my nose to remove skin cancer, creating an incision on my nose from the bridge down to the middle. I was feeling pretty down until I started using PDRN on my nose every night before bed and everyday I noticed the swelling diminished and the incision healing quickly. Within weeks, I looked and felt like me again.
This night cream is AMAZING. It works all night long to allow you to wake up glowing!
Love the glow results
I have been using this product for 3 years and my face has changed dramatically!! My face is hydrated and many fine lines are gone..The texture of my face is tighter and vibrant.
God bless Sesha!!
I LOVE this product. It is because it delivers the amazing results of SPA like clean exfoliation INSTANTLY at HOME. It became an easy and quick addition to my daily skincare routines instead of having to set an extra time for it. Because it clears my skin, it gives other skincare products work better and maximize the outcomes - that also includes foundation. Ever since I start using this product, I receive many compliments on my skin how clean and young it looks. I have been a long time Sesha customer, and I must say this product is one of my favorites! Thank you, Sesha, for always developing great products!
I had years of hands problems, mainly from eczema and washing my hands so often. My hands get dry quickly and get many small painful cuts easily and they do not heal well. The conditions got worse to the point I had to wear disposable gloves to do many daily tasks (even in shower!) just to minimize washing my hands. I tried just about every hand lotions, but none of them really worked. Then I started to use Sesha's Active Recovery Hand Cream, because I realized what my hands really need is a recovery of the new skin layers under the outer skins. With their PET delivery system, the new skin will be nurished, helping it become stronger by the time it becomes the outer layer. Many hand creams for my hand conditions work as a "moisturizer and protective cover" on the outer surface. So once hands are washed, they are gone and hands are still suffering from the same symptoms. My experience with Sesha's hand cream has been great and amazing - it makes my hands look younger, moisturized AND stronger from within. I do not wear these gloves anymore. I highly recommend this product to anyone with hand issues like mine.
I love this lip treatment. very hydrating
I still remember hearing about SESHA Skin Therapy for the first time on 1210 WIP Philadelphia radio, nearly 20–30 years ago. What caught my attention was their unique penetration technology, and since I had just started noticing dark sun spots on my face, I thought maybe SESHA could help me.
Sure enough, it did. I began using the SESHA Skin Lightening Serum with Plus Emulsion back then — and here I am, more than 20 years later, still using it faithfully. Over the years, I’ve added few other products with Sunscreen, and they’ve become a trusted part of my daily routine.
What makes SESHA special isn’t just the products, but also the people behind them. I’ve gotten to know some of the staff who process my orders, and although I’m older than most of them (except the owner), they’ve always treated me like a friend. Thank goodness SESHA is still here and getting stronger — not many skincare brands last this long. I believe it’s because their formulas are truly science-based skincare.
At 78, most people are surprised when they learn my age, and I credit SESHA for keeping my skin looking healthy and vital. I’m grateful not only for the products but also for the thoughtful birthday wishes and gift card they sent me. It’s been an incredible journey with SESHA, and I’m proud to say I’ve been a loyal customer for over two decades.
I still remember hearing about SESHA Skin Therapy for the first time on 1210 WIP Philadelphia radio, nearly 20–30 years ago. What caught my attention was their unique penetration technology, and since I had just started noticing dark sun spots on my face, I thought maybe SESHA could help me.
Sure enough, it did. I began using the SESHA Skin Lightening Serum back then — and here I am, more than 20 years later, still using it faithfully. Over the years, I’ve added the Plus Emulsion and Sunscreen, along with a few other products, and they’ve become a trusted part of my daily routine.
What makes SESHA special isn’t just the products, but also the people behind them. I’ve gotten to know some of the staff who process my orders, and although I’m older than most of them, they’ve always treated me like a friend. Thank goodness SESHA is still here and getting stronger — not many skincare brands last this long. I believe it’s because their formulas are truly science-based skincare.
At 78, most people are surprised when they learn my age, and I credit SESHA for keeping my skin looking healthy and vital. I’m grateful not only for the products, but also for the thoughtful birthday wishes and gift card they sent me. It’s been a wonderful journey with SESHA, and I’m proud to say I’ve been a loyal customer for over two decades.
One of my favorite serums. Perfect for keeping the free radicals away and love the advance ingredients that help enhance my natural skin’s barrier.
I started using SESHA back in 2000 after my sister, who is an esthetician, introduced me to it. I'm almost 80 now and live in a 55+ community—and no one ever guesses my age correctly! I’ve been a longtime fan of the Advanced Antioxidant Cream and Complex C, which I started using from the very beginning.
Recently, I decided to try the beautiful gold bottle—STEM Booster (I like to call it my “gold cream”). Honestly, I didn’t think my skin could improve much more at this age, but I was pleasantly surprised. Within just a week or two, I noticed a healthy glow and smoother texture.
I love this product—and really, the entire SESHA line. It's been a part of my skincare routine for decades, and I wouldn’t go without it!
My mom gave me a bottle of Complex-A and kept raving about how amazing SESHA is. I figured I’d give it a shot to see if it really lived up to the hype—and honestly, she might be onto something. The texture is light, which I like, and it works surprisingly well on my combo skin (still oily in spots, but also dry patches here and there).
After a few weeks, I noticed my skin felt smoother and more balanced. I’ve been using it every night now—though I definitely need to add a bit of moisturizer when the weather gets cold. I’m planning to stick with it and see where it takes me. I mean, I’m still a ways off from worrying too much about aging, but if it keeps my skin looking good like it seems to have done for my mom (her skin looks great for her age), I’m all for it. Not totally sure what else she’s using from SESHA, but clearly, it’s working!
Many good things to say about this product: distributes well on face, very gentle & cleans thoroughly!
Plus - Active Hydra Lotion - Wholesale
Clinical - Advanced Antioxidant Cream - Wholesale
Contact us
Our Corporate Office
1155 Phoenixville Pike, Suite #101
West Chester, PA 19380
Office: 610-355-2454
order@seshaskin.com
Shop by Skin Concern at Sesha Skin Therapy
Whether your skin suffers from acne, dryness, signs of aging, or dehydration, we are here to alleviate all your skin troubles. We offer a range of the best skincare products that are specially formulated to target common skin issues. Browse through our online store to find cleansers, masks, eye creams, vitamin serum for skin, moisturizers, sunscreens, exfoliants and much more. From acne-prone to sensitive skin, we have a collection of bio skincare products just for you.
Discover the Best Skincare Products just for you.
At Sesha Skin Therapy, we believe that your skin is at its healthiest only when it is treated with safe, nourishing ingredients, and that’s what we aim to do. We are committed to using only ingredients that benefit the health and appearance of your skin and eliminate all common concerns.
Made using the patented revolutionary Permeation Enhancement Technology (P.E.T.®), our products are formulated to allow the anti-aging ingredients to effectively penetrate the regenerative layer of the epidermis where new cells are created.
One of the most crucial things when shopping for skincare is approaching it individually. Remember when it comes to finding products to treat your acne or irritation, there is no one-size-fits-all solution. There is a different product and a different routine for each concern, and more importantly, what works for someone else may not necessarily work for you. This is why you should be careful when shopping for skincare products to make sure that you get the right ingredients for your skin. Luckily, our detailed product description makes this process a lot less intimidating, allowing you to make a more confident choice.
If you have any questions or would like to know more about our products, feel free to get in touch with us here. Shop now and get the best anti-aging products.
