Science

What makes SESHA SKIN THERAPY stand apart is our patented delivery system, Permeation Enhancement Technology (PET™).

How PET works

PET™ works by increasing the solubility parameter of the skin so when larger-molecule, active ingredients are combined with PET™, they are able to pass between the skin cell barrier to reach the deeper layers of the skin. This is critical because the surface of the skin, the epidermis, is composed of dying or already dead cells, so the key to healthy skin must start from below. The versatility of PET™ allows us to combine nutrients that work together as a networking system in providing you the full benefits of each individually picked ingredient.

Because PET™ belongs to a family of compounds originally found in nature, PET™ also passes the stringent requirements of the FDA to be considered GRAS (Generally Regarded As Safe), and is non-toxic, non-irritating and non-allergenic. 

The first prescription requiring pharmaceutical product containing PET™ was approved by the FDA in 2002.  PET™ is one of very few transdermal delivery systems which is also safely and effectively used in cosmeceutical products. 

Clinical studies show that 260-350% more vitamins are able to pass through the epidermis with PET™ and that our skin therapy formulations are more than twice as effective than other leading products in reducing the signs of skin damage and aging.

Presentation of Our Patented Delivery System

David Kung's presentation at 2006 ASAPS

Penetration of Active Ingredients

PET technology